Department of Oncology
Dr. Wei Xu (left) and new Komen Fellow Dr. Eui-Jun Kim (right). Eui-Jun Kim, a post-doctoral fellow training in the laboratory of Wei Xu (Messerschmidt Professor of Oncology), was awarded a $185,000 research fellowship from the Susan G. Komen Foundation to study triple-negative breast cancer, a devastating subtype of breast cancer for which the only …
Teriflunomide inhibits the growth of EBV-transformed cells in a mouse model. Immune-deficient mice were injected under the skin on their flanks with cells carrying luminescent EBV. Once a small tumor had grown, mice were treated with teriflunomide three times per week. This image shows the amount of luminescence 13 days after treatment was started. Purple …
Every year, Sun Prairie High School seniors decide on a way they would like to give back to their community before graduation. Two beloved faculty members at Sun Prairie had recently passed away due to cancer, motivating the 2017 graduating class to focus their donation on supporting cancer research at McArdle. “Every student in our high school had known at least one of the …
Dr. Megan Spurgeon, a scientist in Dr. Paul Lambert’s group, is the first recipient at the University of Wisconsin of an R50 Research Specialist Award. This new funding mechanism from the National Cancer Institute seeks to “encourage the development of stable research career opportunities for exceptional scientists who want to pursue research within the context of an existing cancer research …
Expression of both HPV oncogenes E6/E7 and estrogen (E2) alter host gene expression in the cervical stroma. The Venn diagrams and pie charts in this figure show the differential expression of genes in the stroma for E6/E7, E2, and E6/E7+E2 compared to WT mice. From Spurgeon et al., PNAS. 2017 Oct 9; 114(43): E9076-E9085. Human …
Dr. Xu and her lab group. From left to right: Kristine Donahue, lead author Fabao Liu, author Yidan Wang, Justine Coburn, Carlos Coriano, senior author Wei Xu, Steve Chan, Eui-Jun Kim, and Dominic Dharam. Contributing scientists not pictured: Fengfei Ma, Yuyuan Wang, Ling Hao, Hao Zeng, Chenxi Jia, Peng Liu, Irene M. Ong, Baobin Li, Guojun …
Prior to 2003, there was almost no multiple myeloma (MM) research ongoing at UW–Madison. However, the Trillium Fund was established that year by several generous patients to support myeloma research at the UW Carbone Cancer Center. In 2004, Dr. Natalie Callander was recruited to the UW–Madison and the Multiple Myeloma Working Group was established. Now, the …
Roz Boutwell and Alex Law On June 6, 2014, Dr. Roswell “Roz” Boutwell gave a talk on McArdle’s early history. Dr. Boutwell had joined McArdle in 1945, and was one of the core faculty members who helped transform McArdle into a leading cancer research institute. His talk highlighted his role along with the role of …
Wei Xu, right, with McArdle Director Paul Lambert and Ron and Ruth Niendorf. Mr. and Mrs. Niendorf were friends and neighbors of Marian Burgenske, and helped her establish the endowment for Dr. Xu’s professorship. McArdle is excited to announce that Wei Xu has been named the new Marian A. Messerschmidt Professor in Cancer Research. Dr. Xu, who has been a faculty …
Research that began at the McArdle Laboratory for Cancer Research and the UW Carbone Cancer Center decades ago has led to a promising clinical trial for women in parts of the developing world, and could lead to more treatment options for cervical cancer all over the world. View the Full Article