Department of Oncology
Dr. Megan Spurgeon (left) and Dr. Paul Lambert (right) McArdle researchers have developed a model of papillomavirus sexual transmission using the recently discovered murine (mouse) papillomavirus. This new model finally allows research on areas of papillomavirus infection and sexual transmission that have previously not been possible in a small animal model. The paper has recently …
Dr. Megan Spurgeon, Associate Scientist, teaching about the link between viruses and cancer at Saturday Science at Discovery. On Saturday, September 14th, volunteers from the McArdle Laboratory and the Institute for Molecular Virology teamed up to teach children and families from the community about viruses and cancer at the Morgridge Institute’s Saturday Science at Discovery …
Dr. Shannon Kenney Receiving three federal grants from the National Institutes of Health (NIH) within a year is nearly unheard of in the research world, but not for Dr. Shannon Kenney who was awarded two grants from the National Cancer Institute (NCI) and a third from the National Institute of Allergy and Infectious Diseases (NIAID) …
1939 Harold P. Rusch showed that a high-fat or high-calorie diet accelerated the production of cancer in mice. 1940 McArdle Laboratory was established as the first basic cancer research facility in an academic institution in the United States. 1941 Harold P. Rusch found the wavelength of ultraviolet light that produces skin cancer. 1950s – 1970s Elizabeth C. and James …
Researchers Caroline Alexander (left) and Ildiko Kasza (right). Recent discoveries from Caroline Alexander and Ildiko Kasza suggest that skin might be a more important player in metabolism than previously understood. Loss of heat through skin, predominantly by evaporation, may throw a metabolic switch that determines whether mammals lay down body fat and become obese. Their …
Paul Ahlquist speaking in the video on broad-spectrum antivirals and the Morgridge Institute for Research. Dr. Paul Ahlquist speaks about our constant fight against emerging viruses in a video and article originally posted by the Morgridge Institute for Research. “Viruses evolve at phenomenal rates,” noted Ahlquist, adding that “the viruses are winning, but in an …
Howard Temin, photo from the Nobel Foundation archive “Throughout the 1970s, a biologist named Howard Temin became convinced that something wasn’t right in science’s understanding of viruses. His colleagues dismissed him as a heretic. He turned out to be right.” – Malcolm Gladwell Revisionist History Season 4, Episode 10 podcast “The Obscure Virus Club”exposes listeners to …
Left to right: Don Fechner, Karen Schwarz, and Richard Burgess at Don’s 90th birthday celebration on Sunday, August 18, 2019. Don Fechner turned 90 years on September 11, 2019. McArdlites who shared any time at the lab with Don agree that he is incredibly kind and was an invaluable member of the McArdle team. He …
Unequal segregation of chromosomes during cell division is called aneuploidy and can contribute to cancer (left). Aussie Suzuki uses his optimized microscopy method to map out the kinetochore proteins that have an important role in the dividing process (right). Dr. Aussie Suzuki, a new faculty member in the McArdle Laboratory, is utilizing an optimized method …
Aurélia Faure, the paper’s first author, holding cell cultures. Primary Effusion Lymphomas (PELs) are a highly aggressive blood cancer found in immunosuppressed individuals, such as people living with HIV, that researchers have long struggled to study due to the difficulty of developing similar cells in the lab. The lymphomas kill patients within six months of …