
The central mission of the McArdle Laboratory for Cancer Research is twofold:
- To pursue outstanding research programs directed toward understanding the causes and biology of cancer and the factors that regulate normal and neoplastic growth and differentiation.
- To provide training of the highest quality in basic cancer research at the graduate and postdoctoral levels.
While these two goals represent the cornerstone of our activities, we also seek to provide undergraduates and medical students with a foundation in basic cancer biology and to serve the public and scientific community through our activities for national and international organizations. You can see more on our training and instruction here.
During the past 75 years, more than 1800 women and men have received pre- and post-doctoral training at McArdle. Many of these alumni now hold faculty positions at universities throughout the United States and abroad, and most of the others are doing research at research institutes or in government or industry laboratories.
The current staff of the McArdle Laboratory numbers approximately 200. The 27 faculty and emeritus faculty lead 22 research groups that include 68 graduate students, 31 postdoctoral fellows, and 45 research specialists or other academic staff. Other members of the laboratory include the administrative and support personnel and many undergraduates who perform both research and support activities.
Recent News
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McArdle Monthly: August 2026
NF-κB/RelA Signaling Required for CD40-Induced Humoral Immunity Depends on Specific NEMO Lysine Residues in Mice. The NF-κB signaling pathway serves several key purposes in biology, often focused on immune cells. Using their…
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Carstyn Joiner Awarded National Cancer Institute F31 Fellowship
McArdle graduate student Carstyn Joiner has been awarded a Kirschstein-NRSA Predoctoral Fellowship (F31) from the National Cancer Institute (NCI). The F31 fellowship is designed to support specialized training for promising graduate students…
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McArdle Monthly: July 2026
Spurgeon ME, Lange TE, Baty A, Li H, Lambert PF, Setchell KDR, Wells SI, Zhao X. Lipid reprogramming of stratified squamous epithelium by the high-risk HPV E6 and E6/E7 oncoproteins. Metabolomics. 2026…
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McArdle Monthly: June 2026
Umar SA, Wang W, Jeon D, Pham LK, Ward-Shaw ET, Lee D, Hu R, Bilger A, Spurgeon ME, Lambert PF. Estrogen receptor α (Esr1) mediates estrogen’s ability to promote papillomavirus-induced cutaneous disease…
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