McArdle Faculty
Paul Ahlquist
We are studying the novel, RNA-based pathways and virus-host interactions underlying replication, gene expression and evolution by positive-strand RNA viruses, the largest class of viruses.
Caroline Alexander
We study aspects of metabolic physiology that govern tumor susceptibility, notably the role of skin as a modifier of systemic metabolism.
Christopher Bradfield
Our laboratory is interested in a family of transcriptional regulators known as PAS proteins.
Jane Churpek
Our lab is focused on defining the contribution of rare genetic variation to risk of blood disorders and cancer.
Dustin Deming
Our laboratory is investigating kinase modulation of cellular signaling pathways driven by oncogenic mutant proteins
Huy Q. Dinh
Our goal is to understand how tumor immune microenvironment changes toward finding immunotherapeutic biomarkers and targets.
The research in our laboratory is designed to enable cells to protect their genomes against toxic molecules, whether the toxins are encountered during cancer therapy, normal oxidative life, organ transplant or heart attack, or exposure to ionizing radiation.
Eric Johannsen
Our research focuses on the molecular biology of Epstein-Barr virus (EBV) nuclear proteins, their role in the virus lifecycle and the pathogenesis of EBV associated malignancies.
Rob Kalejta
Our lab focuses on determining the mechanisms of human cytomegalovirus (HCMV) replication and pathogenesis, and also uses the virus as a tool to probe the pathways that lead to cell cycle progression and oncogenesis.
Shannon Kenney
Our lab focused upon understanding the molecular regulation and pathogenesis of the human herpesvirus, Epstein-Barr virus (EBV).
Paul Lambert
Our lab’s research is focused on understanding the role of human papillomavirus (HPV) in cancer.
Wenwei Li
Our laboratory investigates the molecular and structural mechanisms of virus–host interactions, with a particular focus on how viruses recognize and enter host cells
Kinjal Majumder
We study how viruses localize to cellular sites on the host genome to establish infection by hijacking the cell’s replication and repair machinery.
Nathan Sherer
Our group is interested in the cell biology underlying the assembly and spread of the human immunodeficiency virus type 1 (HIV-1), the etiological agent causing the acquired immunodeficiency syndrome (AIDS).
Megan Spurgeon
The Spurgeon Lab studies two different small DNA tumor viruses: Merkel cell polyomavirus (MCPyV) and human papillomaviruses (HPVs).
Bill Sugden
Our research focuses on two facets of EBV pivotal to its inducing and maintaining human tumors.
Aussie Suzuki
Our lab focuses on discovering the molecular mechanisms underlying force production, mitotic checkpoint control, and error correction in accurate cell division.
Beth Weaver
Our lab is determining the consequences of mitotic defects on tumor initiation, progression and response to chemotherapy,
Yongna Xing
Our lab studies elucidation of signaling pathways related to cancer using multi-disciplinary biophysics and biochemical approaches, including structural biology and proteomics, in combination with cell biology.
Wei Xu
Our lab focuses on the transcriptional regulation of estrogen receptor (ER) signaling pathways by nuclear receptor co-factors.
Jing Zhang
Our lab focuses on studying the mechanisms underlying the normal as well as oncogenic self-renewal of stem cells using the hematopoietic compartment as a model system.
