Lambert Lab Shows HPV Works Across Cellular Borders to Drive Cervical Cancer
Expression of both HPV oncogenes E6/E7 and estrogen (E2) alter host gene expression in the cervical stroma. The Venn diagrams and pie charts in this figure show the differential expression of genes in the stroma for E6/E7, E2, and E6/E7+E2 compared to WT mice. From Spurgeon et al., PNAS. 2017 Oct 9; 114(43): E9076-E9085. Human …