Department of Oncology
Researchers Caroline Alexander (left) and Ildiko Kasza (right). Recent discoveries from Caroline Alexander and Ildiko Kasza suggest that skin might be a more important player in metabolism than previously understood. Loss of heat through skin, predominantly by evaporation, may throw a metabolic switch that determines whether mammals lay down body fat and become obese. Their …
Paul Ahlquist speaking in the video on broad-spectrum antivirals and the Morgridge Institute for Research. Dr. Paul Ahlquist speaks about our constant fight against emerging viruses in a video and article originally posted by the Morgridge Institute for Research. “Viruses evolve at phenomenal rates,” noted Ahlquist, adding that “the viruses are winning, but in an …
Howard Temin, photo from the Nobel Foundation archive “Throughout the 1970s, a biologist named Howard Temin became convinced that something wasn’t right in science’s understanding of viruses. His colleagues dismissed him as a heretic. He turned out to be right.” – Malcolm Gladwell Revisionist History Season 4, Episode 10 podcast “The Obscure Virus Club”exposes listeners to …
Left to right: Don Fechner, Karen Schwarz, and Richard Burgess at Don’s 90th birthday celebration on Sunday, August 18, 2019. Don Fechner turned 90 years on September 11, 2019. McArdlites who shared any time at the lab with Don agree that he is incredibly kind and was an invaluable member of the McArdle team. He …
Unequal segregation of chromosomes during cell division is called aneuploidy and can contribute to cancer (left). Aussie Suzuki uses his optimized microscopy method to map out the kinetochore proteins that have an important role in the dividing process (right). Dr. Aussie Suzuki, a new faculty member in the McArdle Laboratory, is utilizing an optimized method …
Aurélia Faure, the paper’s first author, holding cell cultures. Primary Effusion Lymphomas (PELs) are a highly aggressive blood cancer found in immunosuppressed individuals, such as people living with HIV, that researchers have long struggled to study due to the difficulty of developing similar cells in the lab. The lymphomas kill patients within six months of …
Janesville Summer Research Institute students at the McArdle Laboratory for Cancer research (7/25). Last Thursday, students from the Janesville Summer Research Institute visited the McArdle Laboratory. The six-week program is headed by Dr. Zach Pratt, a researcher and former graduate student at McArdle. Throughout the course, the students learned about bacteria, viral infections, and genetics. …
Dr. Yongna Xing and Jordan Lang, March 2019 in front of angel’s wings made by patient families. Jordan’s parents spent years visiting doctors to find out why their baby girl wasn’t meeting developmental milestones. After getting a diagnosis in 2016 by whole-exome sequencing, they began connecting researchers and patient families to collaborate and learn more …
Errors in cell division can cause cancer. Here, chromosomes in blue are being pulled in the wrong directions by the microtubules in red which will result in aneuploidy. Photo by Ryan A. Denu of the UW Carbone Cancer Center and the National Cancer Institute Dr. Aussie Suzuki is studying the fundamental mechanisms of cell division to …
The program project grant team (left to right): Nathan Sherer, PhD, Shannon C. Kenney, MD, Paul F. Lambert, PhD ’85, Janet E. Mertz, PhD, Eric C. Johannsen, MD, Paul Ahlquist, PhD ’81, Daniel Loeb, PhD, and Bill Sugden, PhD. 2018-19 was a banner year for McArdle’s Cancer Virology program. First, the program renewed a ~$10 …