Department of Oncology
Dr. Yongna Xing with lead author Cheng-Guo Wu A new study by University of Wisconsin–Madison researchers identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated. The structure explains why the complexes are less active in some cancers and neurodegenerative diseases, and offers a starting point to identify drug …
Left: a papillomavirus. Right: dioxins, polycyclic aromatic hydrocarbons (AHRs), and polychlorinated biphenyls (PCBs). PAS proteins regulate a variety of downstream responses to these three molecules, some of which are toxic effects. McArdle is pleased to announce that Paul Lambert and Chris Bradfield recently received Outstanding Investigator (R35) Awards from the National Institutes of Health. The R35 award is designed to support …
Scientists at the Morgridge Institute for Research have discovered a promising new target to fight a class of viruses responsible for health threats such as Zika, polio, dengue, SARS and hepatitis C. Masaki Nishikiori, a researcher in the Morgridge Institute virology group led by Paul Ahlquist, Morgridge investigator and professor of oncology and molecular virology at the University …
A stone dedicated by Blobel to his mentor Van Potter outside the McArdle Laboratory Building (1400 University Ave) The McArdle Laboratory mourns the loss of Günter Blobel, Nobel Prize-winning cell biologist who discovered and characterized how proteins are targeted within cells. Blobel was one of the most successful graduates of UW–Madison’s long-running Cancer Biology Graduate Training Program, started …
This spring, the University of Wisconsin is offering a new course for graduate students within the Cancer Biology Training Program and other biology graduate programs to effectively apply bioinformatics approaches to their research. The course, “Bioinformatics for Biologists”, is being team-taught by Eric Johannsen, M.D. and Mitchell Hayes. Dr. Johannsen is a faculty member at McArdle, …
McArdle Laboratory Director Dr. Paul Lambert (left) and UW School of Medicine and Public Health Dean Dr. Robert Golden (right) speak at the Night of Hope event. On January 19th, McArdle students, staff, and faculty gathered together with teachers, staff, and supporters from Verona Area High School at Gray’s Tied House for the 13th Annual “Night of Hope” fundraiser. …
McArdle Laboratory and Department of Medicine scientist Dusty Deming knew he wanted to be a physician ever since he was in grade school. Since then, his desire to positively impact the lives of patients as both a clinician and a researcher has been reinforced many times over. During his first semester of medical school at …
We are pleased to announce that McArdle Laboratory alumnus Dr. Lynne Maquat has been awarded the 2018 Wiley Prize in Biomedical Sciences. This prestigious honor is awarded annually to one or more premiere scientists by the Wiley Foundation to “recognize and foster ongoing excellence in scientific achievement and discovery.” Dr. Maquat was awarded the prize for her work elucidating the …
Professor of Oncology Dr. Norman Drinkwater is currently serving as Interim Vice Chancellor for Research and Graduate Education at UW–Madison, replacing Dr. Marsha Mailick (School of Social Work) who is on temporary leave from her vice chancellor duties. Prior to the appointment, Drinkwater had been serving as Associate Vice Chancellor for Research in the Biological Sciences since 2015. Previously, …
Cellular and molecular biology graduate student Adhithi Rajagopalan, a student in the lab of Jing Zhang, PhD at the McArdle Laboratory for Cancer Research, recently presented at the American Association of Cancer Research’s annual conference in Chicago. Rajagopalan’s presentation was part of a scientific session focused on animal models of cancer. UW Carbone physician-scientist Fotis Asimakopoulos, MD, PhD, a collaborator of …