Department of Oncology
Dr. Wei Xu (front row, third from the right) with her fellow awardees at the AACR Grants Reception and Dinner on April 2, 2019. Photo by © AACR/Matt Herp 2019. Wei Xu and her laboratory have been awash in a wave of recent successes, receiving multiple funding awards for their investigations into estrogen signaling and breast …
Dr. F. Michael Hoffmann, a co-principal investigator on the UW2020 grant Anti-cancer drugs, antibiotics or other drugs have always been a key tool at doctors’ disposal for treating patients with a range of diseases. However, the first step in finding molecules that eventually make it to the clinic is both expensive and time-consuming, so anything …
A five-year, $3 million grant from the National Cancer Institute will support UW Carbone Cancer Center physician-researcher and McArdle Laboratory for Cancer Research faculty member Dr. Dusty Deming and colleagues in their pursuit of more effective treatments for colorectal-cancer patients. With the funding, researchers at the McArdle Laboratory for Cancer Research and UW Carbone will grow colon cancer cells from patient-derived tissue …
A sampling of the goods created by the Family Crafters In Brillion, WI, an amazing family works throughout the year to create craft goods to sell at farmers’ markets, craft shows, and grocery stores. Together, they are the Family Crafters, using their time and talents to raise money for cancer research in a unique and …
Dr. Yongna Xing with lead author Cheng-Guo Wu A new study by University of Wisconsin–Madison researchers identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated. The structure explains why the complexes are less active in some cancers and neurodegenerative diseases, and offers a starting point to identify drug …
Left: a papillomavirus. Right: dioxins, polycyclic aromatic hydrocarbons (AHRs), and polychlorinated biphenyls (PCBs). PAS proteins regulate a variety of downstream responses to these three molecules, some of which are toxic effects. McArdle is pleased to announce that Paul Lambert and Chris Bradfield recently received Outstanding Investigator (R35) Awards from the National Institutes of Health. The R35 award is designed to support …
Scientists at the Morgridge Institute for Research have discovered a promising new target to fight a class of viruses responsible for health threats such as Zika, polio, dengue, SARS and hepatitis C. Masaki Nishikiori, a researcher in the Morgridge Institute virology group led by Paul Ahlquist, Morgridge investigator and professor of oncology and molecular virology at the University …
A stone dedicated by Blobel to his mentor Van Potter outside the McArdle Laboratory Building (1400 University Ave) The McArdle Laboratory mourns the loss of Günter Blobel, Nobel Prize-winning cell biologist who discovered and characterized how proteins are targeted within cells. Blobel was one of the most successful graduates of UW–Madison’s long-running Cancer Biology Graduate Training Program, started …
This spring, the University of Wisconsin is offering a new course for graduate students within the Cancer Biology Training Program and other biology graduate programs to effectively apply bioinformatics approaches to their research. The course, “Bioinformatics for Biologists”, is being team-taught by Eric Johannsen, M.D. and Mitchell Hayes. Dr. Johannsen is a faculty member at McArdle, …
McArdle Laboratory Director Dr. Paul Lambert (left) and UW School of Medicine and Public Health Dean Dr. Robert Golden (right) speak at the Night of Hope event. On January 19th, McArdle students, staff, and faculty gathered together with teachers, staff, and supporters from Verona Area High School at Gray’s Tied House for the 13th Annual “Night of Hope” fundraiser. …