Department of Oncology
Spurgeon ME, Lange TE, Baty A, Li H, Lambert PF, Setchell KDR, Wells SI, Zhao X. Lipid reprogramming of stratified squamous epithelium by the high-risk HPV E6 and E6/E7 oncoproteins. Metabolomics. 2026 Jul 1;22(4):111. doi: 10.1007/s11306-026-02498-2. PMID: 42384270; PMCID: PMC13323514. Viruses cleverly manipulate their host cells to support their maintenance, replication and spread. Genes and …
Umar SA, Wang W, Jeon D, Pham LK, Ward-Shaw ET, Lee D, Hu R, Bilger A, Spurgeon ME, Lambert PF. Estrogen receptor α (Esr1) mediates estrogen’s ability to promote papillomavirus-induced cutaneous disease in male and female mice. mBio. 2026 May 29:e0078326. doi: 10.1128/mbio.00783-26. Epub ahead of print. PMID: 42212803. Tumors of reproductive tissues often use …
Deming DA, Kraus SG, Brand J, Johnson KA, Abbott D, Kratz J, Turk AA, Emmerich P, Carchman E, Lubner SJ, LoConte NK, Uboha NV, Chaudhuri S, Shah R, Field A, Field E, Pasch CA, Kim DH, Weber S, Heise C, Lawson E, Sanger C, Matkowskyj K, Asimakopoulos F, Eickhoff J, Dinh HQ, Bassetti MF. Tumor …
In the past school year students at Freedom High School raised and donated over $14,000 for cancer research at the McArdle Laboratory for Cancer Research. The Freedom community, a town of ~6300 residents located between Appleton and Green Bay, has supported the students and their efforts to raise funds for cancer research for well over …
Monday, May 18, 2026 12:00 PM Precision Medicine Seminar Series: Liquid Biopsy Approaches for Monitoring Infectious and Inflammatory Diseases; Speaker: Dr. Iwijn De Vlaminck, Professor in the Meinig School of Biomedical Engineering at Cornell University. Join in person: 2798 WIMR West Wedge Room Join via Zoom: https://uwmadison.zoom.us/j/94806573353?pwd=p2JDBPbelaAIDgQw6LvIZbv6TTOA8p.1 Tuesday, May 19, 2026 No Seminars Wednesday, May …
McArdle Laboratory for Cancer Research April 2026 Publications Abrahams RR, Larsen CIS, Ha R, Majumder K. The interaction between virus-bound KLF4 and host-bound PARP1 directs the localization of wild-type adeno-associated virus type 2 (wtAAV2) to cellular sites of DNA damage. J Virol. 2026 Apr 29:e0030626. doi: 10.1128/jvi.00306-26. PMID: 42053296. Since adeno-associated viruses (AAVs) are used …
Monday, May 11, 2026 3:00 PM Biochemistry Colloquium: Thriving Under Pressure: Ubiquitin and Translation Reprogramming During Oxidative Stress; Speaker: Gustavo Silva, Duke University. Join in person: 1211 Biochemical Sciences Join online: https://go.wisc.edu/bio_colloq 3:30 PM McArdle Trainee Seminar: Developing novel therapeutic regimens for treating ultra-high risk multiple myeloma; Speaker: Vysakh Anandan, PhD (Zhang Lab); Estrogen Receptor …
Alexandra and Bill Dove spent over 50 years carrying out research at the McArdle Laboratory for Cancer Research. In addition to their scientific accomplishments, they leave behind a legacy of outreach and connection. Now Bill and Alexandra’s granddaughter, Miranda Garcia-Dove, a junior at UW–Madison, is continuing their commitment to bringing people together from diverse backgrounds …
Monday, May 4, 2026 3:00 PM Biochemistry Colloquium: Quantitative Proteomics for Understanding Epigenetic Mechanisms in Human Disease; Speaker: Ben Garcia, Washington University in St. Louis. Join in person: 1211 Biochemical Sciences 3:30 PM McArdle Trainee Seminar: If You Give a Mouse a loxP; Speaker: Maggie Stangis (Advisor: Paul Lambert, PhD); Development of Lytic Induction Therapy …
Monday, April 27, 2026 12:30 PM MCP Signal Transduction Research Symposium Keynote: Non-canonical signaling mechanisms through which glucocorticoids promote drug seeking; Speaker: Dr. John Mantsch, PhD, Medical College of Wisconsin. Join in person: 1325 HSLC 3:00 PM Biochemistry Colloquium: Structural and Dynamic Studies of Protein and Protein-nucleic Acid Complexes by Solid-state NMR; Speaker: Christopher Jaroniec, …