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UW School of Medicine and Public Health
Carbone Cancer Center

2019 McArdle Publications

Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metab. 2019 Feb 18. pii: S1550-4131(19)30063-4. doi: 10.1016/j.cmet.2019.01.023. [Epub ahead of print] PubMed PMID: 30827863.

Chakravorty A, Sugden B, Johannsen EC. An epigenetic journey: Epstein-Barr virus transcribes chromatinized and subsequently unchromatinized templates during its lytic cycle. J Virol. 2019 Jan 30. pii: JVI.02247-18. doi: 10.1128/JVI.02247-18. [Epub ahead of print] Review. PubMed PMID: 30700606.

Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo WGP, Pinto-Tomás AA, Schmitz A, Wendt-Pienkowski E, Wildman S, Zhao M, Zhang F, Bugni TS, Andes DR, Pupo MT, Currie CR. The antimicrobial potential of Streptomyces from insect microbiomes. Nat Commun. 2019 Jan 31;10(1):516. doi: 10.1038/s41467-019-08438-0. PubMed PMID: 30705269; PubMed Central PMCID: PMC6355912.

Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA. MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers. Mol Cancer Ther. 2019 Feb;18(2):346-355. doi: 10.1158/1535-7163.MCT-18-0510. Epub 2018 Nov 13. PubMed PMID: 30425131; PubMed Central PMCID: PMC6363831.

Gorbunova V, Beck JT, Hofheinz RD, Garcia-Alfonso P, Nechaeva M, Cubillo Gracian A, Mangel L, Elez Fernandez E, Deming DA, Ramanathan RK, Torres AH, Sullivan D, Luo Y, Berlin JD. A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer. Br J Cancer. 2019 Jan;120(2):183-189. doi: 10.1038/s41416-018-0343-z. Epub 2018 Dec 11. PubMed PMID: 30531832.

He C, Lv X, Huang C, Angeletti PC, Hua G, Dong J, Zhou J, Wang Z, Ma B, Chen X, Lambert PF, Rueda BR, Davis JS, Wang C. A Human Papillomavirus-Independent Cervical Cancer Animal Model Reveals Unconventional Mechanisms of Cervical Carcinogenesis. Cell Rep. 2019 Mar 5;26(10):2636-2650.e5. doi: 10.1016/j.celrep.2019.02.004. PubMed PMID: 30840887.

Helzer KT, Ozers MS, Meyer MB, Benkusky NA, Solodin N, Reese RM, Warren CL, Pike JW, Alarid ET. The Phosphorylated Estrogen Receptor α (ER) Cistrome Identifies a Subset of Active Enhancers Enriched for Direct ER-DNA Binding and the Transcription Factor GRHL2. Mol Cell Biol. 2018 Nov 19. pii: MCB.00417-18. doi: 10.1128/MCB.00417-18. [Epub ahead of print] PubMed PMID: 30455249; PubMed Central PMCID: PMC6336141.

Kong G, You X, Wen Z, Chang YI, Qian S, Ranheim EA, Letson C, Zhang X, Zhou Y, Liu Y, Rajagopalan A, Zhang J, Stieglitz E, Loh M, Hofmann I, Yang D, Zhong X, Padron E, Zhou L, Pear WS, Zhang J. Downregulating Notch counteracts Kras(G12D)-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm. Leukemia. 2019 Mar;33(3):671-685. doi: 10.1038/s41375-018-0248-0. Epub 2018 Sep 11. PubMed PMID: 30206308; PubMed Central PMCID: PMC6405304.

Liu S, Alnammi M, Ericksen SS, Voter AF, Ananiev GE, Keck JL, Hoffmann FM, Wildman SA, Gitter A. Practical Model Selection for Prospective Virtual Screening. J Chem Inf Model. 2019 Jan 28;59(1):282-293. doi: 10.1021/acs.jcim.8b00363. Epub 2018 Dec 18. PubMed PMID: 30500183; PubMed Central PMCID: PMC6351977.

Lu W, Chen S, Yu J, Behrens R, Wiggins J, Sherer N, Liu SL, Xiong Y, Xiang SH, Wu L. The Polar Region of HIV-1 Envelope Protein Determines Viral Fusion and Infectivity by Stabilizing gp120-gp41 Association. J Virol. 2019 Jan 16. pii: JVI.02128-18. doi: 10.1128/JVI.02128-18. [Epub ahead of print] PubMed PMID: 30651369.

O'Driscoll CA, Owens LA, Hoffmann EJ, Gallo ME, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD. Ambient urban dust particulate matter reduces pathologic T cells in the CNS and severity of EAE. Environ Res. 2019 Jan;168:178-192. doi: 10.1016/j.envres.2018.09.038. Epub 2018 Oct 1. PubMed PMID: 30316103; PubMed Central PMCID: PMC6263800.

Pickhardt PJ, Pooler BD, Matkowskyj KA, Kim DH, Grady WM, Halberg RB. Volumetric growth rates of sessile serrated adenomas/polyps observed in situ at longitudinal CT colonography. Eur Radiol. 2019 Feb 11. doi: 10.1007/s00330-019-5999-0. [Epub ahead of print] PubMed PMID: 30741343.

Pooler BD, Lubner MG, Theis JR, Halberg RB, Liang Z, Pickhardt PJ. Volumetric Textural Analysis of Colorectal Masses at CT Colonography: Differentiating Benign versus Malignant Pathology and Comparison with Human Reader Performance. Acad Radiol. 2019 Jan;26(1):30-37. doi: 10.1016/j.acra.2018.03.002. Epub 2018 Mar 19. PubMed PMID: 29566994.

Shin MK, Payne S, Bilger A, Matkowskyj KA, Carchman E, Meyer DS, Bentires-Alj M, Deming DA, Lambert PF. Activating Mutations in Pik3ca Contribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes. Clin Cancer Res. 2018 Dec 7. doi: 10.1158/1078-0432.CCR-18-2843. [Epub ahead of print] PubMed PMID: 30530704.

Soukup AA, Zheng Y, Mehta C, Wu J, Liu P, Cao M, Hofmann I, Zhou Y, Zhang J, Johnson KD, Choi K, Keles S, Bresnick EH. Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019 Mar 1;129(3):1180-1192. doi: 10.1172/JCI122694. Epub 2019 Feb 11. PubMed PMID: 30620726; PubMed Central PMCID: PMC6391105

Spurgeon ME, Uberoi A, McGregor SM, Wei T, Ward-Shaw E, Lambert PF. A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract. MBio. 2019 Mar 5;10(2). pii: e00180-19. doi: 10.1128/mBio.00180-19. PubMed PMID: 30837335.

You, X., Wen, Z., Chang, Yuan-I, Ranheim, E.A., Zhou, Y., Zhou, L., Kong, G., Zhang, J. Systemic Notch Downregulation Promotes KrasG12D-induced Myeloproliferative Neoplasm. Br. J. Haematol. 2019 in print.

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