UW madison
UW School of Medicine and Public Health
Carbone Cancer Center

2018 McArdle Publications (in progress)

Alexander CM. The Wnt Signaling Landscape of Mammary Stem Cells and Breast Tumors. Prog Mol Biol Transl Sci. 2018 Jan;153:271-298. doi: 10.1016/bs.pmbts.2017.11.020. Epub 2017 Dec 27. PubMed PMID: 29389520.

Benson AB 3rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Garrido-Laguna I, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Freedman-Cass DA. NCCN Guidelines Insights: Colon Cancer, Version 2.2018. J Natl Compr Canc Netw. 2018 Apr;16(4):359-369. doi: 10.6004/jnccn.2018.0021. PubMed PMID: 29632055.

Benson AB 3rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Freedman-Cass DA. Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jul;16(7):852-871. doi: 10.6004/jnccn.2018.0060. PubMed PMID: 30006428.

Benson AB 3rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Gurski L, Freedman-Cass DA. Rectal Cancer, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jul;16(7):874-901.  doi: 10.6004/jnccn.2018.0061. PubMed PMID: 30006429

Bristol JA, Djavadian R, Albright ER, Coleman CB, Ohashi M, Hayes M, Romero-Masters JC, Barlow EA, Farrell PJ, Rochford R, Kalejta RF, Johannsen EC, Kenney SC. A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection. PLoS Pathog. 2018 Jul 27;14(7):e1007179. doi: 10.1371/journal.ppat.1007179. ecollection 2018 Jul. PubMed PMID: 30052684

Burgess RR. A brief practical review of size exclusion chromatography: Rules of thumb, limitations, and troubleshooting. Protein Expr Purif. 2018 Oct;150:81-85. doi: 10.1016/j.pep.2018.05.007. Epub 2018 May 17. Review. PubMed PMID: 29777748.

Chen Z, Yu Q, Hao L, Liu F, Johnson J, Tian Z, Kao WJ, Xu W, Li L. Site-specific characterization and quantitation of N-glycopeptides in PKM2 knockout breast cancer cells using DiLeu isobaric tags enabled by electron-transfer/higher-energy collision dissociation (EThcD). Analyst. 2018 May 29;143(11):2508-2519. doi: 10.1039/c8an00216a. PubMed PMID: 29687791; PubMed Central PMCID: PMC5975206.

Chiu YF, Sugden B. Plasmid Partitioning by Human Tumor Viruses. J Virol. 2018 Apr 13;92(9). pii: e02170-17. doi: 10.1128/JVI.02170-17. Print 2018 May 1. Review. PubMed PMID: 29467315; PubMed Central PMCID: PMC5899212.

Coriano CG, Liu F, Sievers CK, Liang M, Wang Y, Lim Y, Yu M, Xu W. A Computational-Based Approach to Identify Estrogen Receptor α/β Heterodimer Selective Ligands. Mol Pharmacol. 2018 Mar;93(3):197-207. doi: 10.1124/mol.117.108696. Epub 2018 Jan 2. PubMed PMID: 29295894; PubMed Central PMCID: PMC5801554.

Cummings NE, Williams EM, Kasza I, Konon EN, Schaid MD, Schmidt BA, Poudel C, Sherman DS, Yu D, Arriola Apelo SI, Cottrell SE, Geiger G, Barnes ME, Wisinski JA, Fenske RJ, Matkowskyj KA, Kimple ME, Alexander CM, Merrins MJ, Lamming DW. Restoration of metabolic health by decreased consumption of branched-chain amino acids. J Physiol. 2018 Feb 15;596(4):623-645. doi: 10.1113/JP275075. Epub 2017 Dec 27. PubMed PMID: 29266268; PubMed Central PMCID: PMC5813603.

Deming DA. Tailoring the colorectal cancer disease assessment to the treatment strategy. Gut. 2018 Jun;67(6):996-997. doi: 10.1136/gutjnl-2017-315394. Epub 2017 Dec 21. PubMed PMID: 29269439.

Djavadian R, Hayes M, Johannsen E. CAGE-seq analysis of Epstein-Barr virus lytic gene transcription: 3 kinetic classes from 2 mechanisms. PLoS Pathog. 2018 Jun 4;14(6):e1007114. doi: 10.1371/journal.ppat.1007114. eCollection 2018 Jun. PubMed PMID: 29864140; PubMed Central PMCID: PMC6005644.

Dugan JP, Haverkos BM, Villagomez L, Martin LK, Lustberg M, Patton J, Martin M, Huang Y, Nuovo G, Yan F, Cavaliere R, Fingeroth J, Kenney SC, Ambinder RF, Lozanski G, Porcu P, Caligiuri MA, Baiocchi RA. Complete and Durable Responses in Primary Central Nervous System Posttransplant Lymphoproliferative Disorder with Zidovudine, Ganciclovir, Rituximab, and Dexamethasone. Clin Cancer Res. 2018 Jul 15;24(14):3273-3281. doi: 10.1158/1078-0432.CCR-17-2685. Epub 2018 Apr 9. PubMed PMID: 29632007; PubMed Central PMCID: PMC6050103.

Evans EL 3rd, Becker JT, Fricke SL, Patel K, Sherer NM. HIV-1 Vif's Capacity To Manipulate the Cell Cycle Is Species Specific. J Virol. 2018 Mar 14;92(7). pii: e02102-17. doi: 10.1128/JVI.02102-17. Print 2018 Apr 1. PubMed PMID: 29321323; PubMed Central PMCID: PMC5972884.

Finlin BS, Memetimin H, Confides AL, Kasza I, Zhu B, Vekaria HJ, Harfmann B, Jones KA, Johnson ZR, Westgate PM, Alexander CM, Sullivan PG, Dupont-Versteegden EE, Kern PA. Human adipose beiging in response to cold and mirabegron. JCI Insight. 2018 Aug 9;3(15). pii: 121510. doi: 10.1172/jci.insight.121510. [Epub ahead of print] PubMed PMID: 30089732.

Garcia-Ruiz H, Diaz A, Ahlquist P. Intermolecular RNA Recombination Occurs at Different Frequencies in Alternate Forms of Brome Mosaic Virus RNA Replication Compartments. Viruses. 2018 Mar 15;10(3). pii: E131. doi: 10.3390/v10030131. PubMed PMID: 29543718; PubMed Central PMCID: PMC5869524.

Hoebe E, Wille C, Hagemeier S, Kenney S, Greijer A, Middeldorp J. Epstein-Barr Virus Gene BARF1 Expression is Regulated by the Epithelial Differentiation Factor ΔNp63α in Undifferentiated Nasopharyngeal Carcinoma. Cancers (Basel). 2018 Mar 17;10(3). pii: E76. doi: 10.3390/cancers10030076. PubMed PMID: 29562599; PubMed Central PMCID: PMC5876651.

Huynh M, Pak C, Markovina S, Callander NS, Chng KS, Wuerzberger-Davis SM, Bakshi DD, Kink JA, Hematti P, Hope C, Asimakopoulos F, Rui L, Miyamoto S. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma. J Biol Chem. 2018 Feb 16;293(7):2452-2465. doi: 10.1074/jbc.RA117.000667. Epub 2017 Dec 26. PubMed PMID: 29279332; PubMed Central PMCID: PMC5818187.

Jallow F, Brockman JL, Helzer KT, Rugowski DE, Goffin V, Alarid ET, Schuler LA. 17β-Estradiol and ICI182,780 Differentially Regulate STAT5 Isoforms in Female Mammary Epithelium, With Distinct Outcomes. J Endocr Soc. 2018 Feb 26;2(3):293-309. doi: 10.1210/js.2017-00399. eCollection 2018 Mar 1. PubMed PMID: 29594259; PubMed Central PMCID: PMC5842396.

Jermusek F Jr, Benedict C, Dreischmeier E, Brand M, Uder M, Jeffery JJ, Ranallo FN, Fahl WE. Significant Suppression of CT Radiation-Induced DNA Damage in Normal Human Cells by the PrC-210 Radioprotector. Radiat Res. 2018 Aug;190(2):133-141. doi: 10.1667/RR14928.1. Epub 2018 May 21. PubMed PMID: 29781766.  PubMed Central PMCID: PMC6083833

Jerry DJ, Shull JD, Hadsell DL, Rijnkels M, Dunphy KA, Schneider SS, Vandenberg LN, Majhi PD, Byrne C, Trentham-Dietz A. Genetic variation in sensitivity to estrogens and breast cancer risk. Mamm Genome. 2018 Feb;29(1-2):24-37. doi: 10.1007/s00335-018-9741-z. Epub 2018 Feb 27. PubMed PMID: 29487996; PubMed Central PMCID: PMC5936622.

Lee SJ, Zea R, Kim DH, Lubner MG, Deming DA, Pickhardt PJ. CT texture features of liver parenchyma for predicting development of metastatic disease and overall survival in patients with colorectal cancer. Eur Radiol. 2018 Apr;28(4):1520-1528. doi: 10.1007/s00330-017-5111-6. Epub 2017 Nov 21. PubMed PMID: 29164382.

Lu Z, Hong CC, Kong G, Assumpção ALFV, Ong IM, Bresnick EH, Zhang J, Pan X. Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence. Cell Rep. 2018 Feb 6;22(6):1545-1559. doi: 10.1016/j.celrep.2018.01.026. PubMed PMID: 29425509.

Lubner S, Feng Y, Mulcahy M, O'Dwyer P, Giang GY, Hinshaw JL, Deming D, Klein L, Teitelbaum U, Payne J, Engstrom P, Stella P, Meropol N, Benson A. E4206: AMG 706 and Octreotide in Patients with Low-Grade Neuroendocrine Tumors. Oncologist. 2018 May 31. pii: theoncologist.2018-0294. doi: 10.1634/theoncologist.2018-0294. [Epub ahead of print] PubMed PMID: 29853660.

Lyon SM, Kalejta RF. HCMV Assembly Is Totally Tubular. Dev Cell. 2018 Apr 9;45(1):1-2. doi: 10.1016/j.devcel.2018.03.014. PubMed PMID: 29634930.

Ma F, Liu F, Xu W, Li L. Surfactant and Chaotropic Agent Assisted Sequential Extraction/On-Pellet Digestion (SCAD) for Enhanced Proteomics. J Proteome Res. 2018 Aug 3;17(8):2744-2754. doi: 10.1021/acs.jproteome.8b00197. Epub 2018 Jul 9.  PubMed PMID: 29923408

McIver SC, Hewitt KJ, Gao X, Mehta C, Zhang J, Bresnick EH. Dissecting Regulatory Mechanisms Using Mouse Fetal Liver-Derived Erythroid Cells. Methods Mol Biol. 2018;1698:67-89. doi: 10.1007/978-1-4939-7428-3_4. PubMed PMID: 29076084; PubMed Central PMCID: PMC5842797.

Meyers JM, Grace M, Uberoi A, Lambert PF, Munger K. Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses. Front Microbiol. 2018 Mar 8;9:389. doi: 10.3389/fmicb.2018.00389. eCollection 2018. Review. PubMed PMID: 29568286; PubMed Central PMCID: PMC5852067.

Morgan MM, Livingston MK, Warrick JW, Stanek EM, Alarid ET, Beebe DJ, Johnson BP. Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model. Sci Rep. 2018 May 8;8(1):7139. doi: 10.1038/s41598-018-25461-1. PubMed PMID: 29740030; PubMed Central PMCID: PMC5940820.

Munguía-Moreno JA, Díaz-Chavéz J, García-Villa E, Albino-Sanchez ME, Mendoza-Villanueva D, Ocadiz-Delgado R, Bonilla-Delgado J, Marín-Flores A, Cortés-Malagón EM, Alvarez-Rios E, Hidalgo-Miranda A, Üren A, Çelik H, Lambert PF, Gariglio P. Early synergistic interactions between the HPV16‑E7 oncoprotein and 17β-oestradiol for repressing the expression of Granzyme B in a cervical cancer model. Int J Oncol. 2018 Aug;53(2):579-591. doi: 10.3892/ijo.2018.4432. Epub 2018 Jun 6. PubMed PMID: 29901186; PubMed Central PMCID: PMC6017153.

Nikodemova M, Yee J, Carney PR, Bradfield CA, Malecki KM. Transcriptional differences between smokers and non-smokers and variance by obesity as a risk factor for human sensitivity to environmental exposures. Environ Int. 2018 Apr;113:249-258. doi: 10.1016/j.envint.2018.02.016. Epub 2018 Feb 16. PubMed PMID: 29459183; PubMed Central PMCID: PMC5866236.

Nishikiori M, Ahlquist P. Organelle luminal dependence of (+)strand RNA virus replication reveals a hidden druggable target. Sci Adv. 2018 Jan 24;4(1):eaap8258. doi: 10.1126/sciadv.aap8258. eCollection 2018 Jan. PubMed PMID: 29387794; PubMed Central PMCID: PMC5787378.

Nyman P, Buehler D, Lambert PF. Loss of Function of Canonical Notch Signaling Drives Head and Neck Carcinogenesis. Clin Cancer Res. 2018 Aug 7. pii: clincanres.3535.2017. doi: 10.1158/1078-0432.CCR-17-3535. [Epub ahead of print] PubMed PMID: 30087145.

Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L. Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype. Aging Cell. 2018 Jul 27:e12820. doi: 10.1111/acel.12820. [Epub ahead of print] PubMed PMID: 30051577.

Pooler BD, Lubner MG, Theis JR, Halberg RB, Liang Z, Pickhardt PJ. Volumetric Textural Analysis of Colorectal Masses at CT Colonography: Differentiating Benign versus Malignant Pathology and Comparison with Human Reader Performance. Acad Radiol. 2018 Mar 19. pii: S1076-6332(18)30114-4. doi: 10.1016/j.acra.2018.03.002. [Epub ahead of print] PubMed PMID: 29566994.

Rodríguez-Uribe G, Serafín-Higuera N, Damian-Morales G, Cortés-Malagón EM, García-Hernández V, Verdejo-Torres O, Campos-Blázquez JP, Trejo-Muñoz CR, Contreras RG, Ocadiz-Delgado R, Palacios-Reyes C, Lambert PF, Griep AE, Mancilla-Percino T, Escobar-Herrera J, Álvarez-Ríos E, Ugarte-Briones C, Moreno J, Gariglio P, Bonilla-Delgado J. HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model. Biomed Res Int. 2018 May 16;2018:2847873. doi: 10.1155/2018/2847873. eCollection 2018. PubMed PMID: 29888254; PubMed Central PMCID: PMC5977056.

Seok SH, Ma ZX, Feltenberger JB, Chen H, Chen H, Scarlett C, Lin Z, Satyshur KA, Cortopassi M, Jefcoate CR, Ge Y, Tang W, Bradfield CA, Xing Y. Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR). J Biol Chem. 2018 Feb 9;293(6):1994-2005. doi: 10.1074/jbc.RA117.000631. Epub 2017 Dec 26. PubMed PMID: 29279331; PubMed Central PMCID: PMC5808761.

Shea MP, O'Leary KA, Fakhraldeen SA, Goffin V, Friedl A, Wisinski KB, Alexander CM, Schuler LA. Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERα(+) Mammary Carcinomas. Cancer Res. 2018 Apr 1;78(7):1672-1684. doi: 10.1158/0008-5472.CAN-17-0985. Epub 2018 Jan 23. PubMed PMID: 29363543; PubMed Central PMCID: PMC5882549.

Shin HC, Deterra D, Park J, Kim H, Nishikiori M, Uetrecht C, Ahlquist PG, Arbulu M, Blick RH. Ultra-high mass multimer analysis of protein-1a capping domains by a silicon nanomembrane detector. J Proteomics. 2018 Mar 20;175:5-11. doi: 10.1016/j.jprot.2017.11.024. Epub 2017 Dec 1. PubMed PMID: 29199149.

Shull JD, Dennison KL, Chack AC, Trentham-Dietz A. Rat models of 17β-estradiol-induced mammary cancer reveal novel insights into breast cancer etiology and prevention. Physiol Genomics. 2018 Mar 1;50(3):215-234. doi: 10.1152/physiolgenomics.00105.2017. Epub 2018 Jan 26. PubMed PMID: 29373076; PubMed Central PMCID: PMC5899232.

Uberoi A, Yoshida S, Lambert PF. Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1). J Virol Methods. 2018 Mar;253:11-17. doi: 10.1016/j.jviromet.2017.12.002. Epub 2017 Dec 15. PubMed PMID: 29253496; PubMed Central PMCID: PMC5898621.

Umaña AC, Iwahori S, Kalejta RF. Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk). ACS Chem Biol. 2018 Jan 19;13(1):189-199. doi: 10.1021/acschembio.7b00972. Epub 2017 Dec 19. PubMed PMID: 29215867; PubMed Central PMCID: PMC5777508.

Voter AF, Killoran MP, Ananiev GE, Wildman SA, Hoffmann FM, Keck JL. A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility. SLAS Discov. 2018 Jan;23(1):94-101. doi: 10.1177/2472555217712001. Epub 2017 Jun 1. PubMed PMID: 28570838; PubMed Central PMCID: PMC5667550.

Wang Q, Jiang J, Ying G, Xie XQ, Zhang X, Xu W, Zhang X, Song E, Bu H, Ping YF, Yao XH, Wang B, Xu S, Yan ZX, Tai Y, Hu B, Qi X, Wang YX, He ZC, Wang Y, Wang JM, Cui YH, Chen F, Meng K, Wang Z, Bian XW. Tamoxifen enhances stemness and promotes metastasis of ERα36(+) breast cancer by upregulating ALDH1A1 in cancer cells. Cell Res. 2018 Mar;28(3):336-358. doi: 10.1038/cr.2018.15. Epub 2018 Feb 2. PubMed PMID: 29393296; PubMed Central PMCID: PMC5835774.

Weng C, Lee D, Gelbmann CB, Van Sciver N, Nawandar DM, Kenney SC, Kalejta RF.  Human Cytomegalovirus Productively Replicates In Vitro in Undifferentiated Oral Epithelial Cells. J Virol. 2018 Jul 31;92(16). pii: e00903-18. doi: 10.1128/JVI.00903-18. Print 2018 Aug 15. PubMed PMID: 29848590.

You JS, Dooley MS, Kim CR, Kim EJ, Xu W, Goodman CA, Hornberger TA. A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling. Sci Signal. 2018 May 15;11(530). pii: eaao6847. doi: 10.1126/scisignal.aao6847. PubMed PMID: 29764991.

Zhang L, Zhou H, Li X, Vartuli RL, Rowse M, Xing Y, Rudra P, Ghosh D, Zhao R, Ford HL. Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression. Nat Commun. 2018 Mar 13;9(1):1047. doi: 10.1038/s41467-018-03327-4. PubMed PMID: 29535359; PubMed Central PMCID: PMC5849647.

Zhao X, Brusadelli MG, Sauter S, Butsch Kovacic M, Zhang W, Romick-Rosendale LE, Lambert PF, Setchell KDR, Wells SI. Lipidomic Profiling Links the Fanconi Anemia Pathway to Glycosphingolipid Metabolism in Head and Neck Cancer Cells. Clin Cancer Res. 2018 Jun 1;24(11):2700-2709. doi: 10.1158/1078-0432.CCR-17-3686. Epub 2018 Mar 12. PubMed PMID: 29530934; PubMed Central PMCID: PMC5984686.

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