UW madison
UW School of Medicine and Public Health
Carbone Cancer Center

2017 McArdle Publications (in progress)

Becker JT, Sherer NM. Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly. J Virol. 2017 Feb 28;91(6). pii: e02315-16. doi: 10.1128/JVI.02315-16. PubMed PMID: 28053097; PubMed Central PMCID:  PMC5331792.

Behrens RT, Aligeti M, Pocock GM, Higgins CA, Sherer NM. Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export. J Virol. 2017 Jan 18;91(3). pii: e02107-16. doi: 10.1128/JVI.02107-16. PubMed PMID: 27852860; PubMed Central PMCID: PMC5244332.

Benson AB 3rd, Venook AP, Cederquist L, Chan E, Chen YJ, Cooper HS, Deming D, Engstrom PF, Enzinger PC, Fichera A, Grem JL, Grothey A, Hochster HS, Hoffe S, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wu CS, Gregory KM, Freedman-Cass D. Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2017 Mar;15(3):370-398. PubMed PMID: 28275037.

Bilger A, Plowshay J, Ma S, Nawandar D, Barlow EA, Romero-Masters JC, Bristol JA, Li Z, Tsai MH, Delecluse HJ, Kenney SC. Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)- induced lymphoproliferative disease and lytic viral replication. Oncotarget. 2017 Jul 4;8(27):44266-44280. doi: 10.18632/oncotarget.17863. PubMed PMID: 28574826; PubMed Central PMCID: PMC5546479.

Buono RA, Leier A, Paez-Valencia J, Pennington J, Goodman K, Miller N, Ahlquist P, Marquez-Lago TT, Otegui MS. ESCRT-mediated vesicle concatenation in plant endosomes. J Cell Biol. 2017 Jul 3;216(7):2167-2177. doi: 10.1083/jcb.201612040. Epub 2017 Jun 7. PubMed PMID: 28592443; PubMed Central PMCID: PMC5496621.

Burgess RR, Watson JD. Gentle antibody-mimetic affinity chromatography with polyol-responsive nanoCLAMPs. Protein Expr Purif. 2017 Jun;134:154-155. doi: 10.1016/j.pep.2017.06.002. PubMed PMID: 28633910.

Burkard ME, Deming DA, Lauring J. Using cancer genomics to guide clinical decisions. Cancer. 2017 Apr 15;123(8):1288-1291. doi: 10.1002/cncr.30640. Epub 2017 Mar 2. PubMed PMID: 28253425.

Chang YI, Kong G, Ranheim EA, Tu PS, Yu YS, Zhang J. Dnmt3a haploinsufficiency cooperates with oncogenic Kras to promote an early-onset T-cell acute lymphoblastic leukemia. Am J Transl Res. 2017 Mar 15;9(3):1326-1334. eCollection 2017. PubMed PMID: 28386358; PubMed Central PMCID: PMC5376023.

Chiu YF, Sugden AU, Fox K, Hayes M, Sugden B. Kaposi's sarcoma-associated herpesvirus stably clusters its genomes across generations to maintain itself extrachromosomally. J Cell Biol. 2017 Sep 4;216(9):2745-2758. doi: 10.1083/jcb.201702013. Epub 2017 Jul 10. PubMed PMID: 28696226.

Clark PA, Gaal JT, Strebe JK, Pasch CA, Deming DA, Kuo JS, Robins HI. The effects of tumor treating fields and temozolomide in MGMT expressing and non-expressing patient-derived glioblastoma cells. J Clin Neurosci. 2017 Feb;36:120-124. doi: 10.1016/j.jocn.2016.10.042. PubMed PMID: 27865821; PubMed Central PMCID: PMC5215614.

Czito BG, Deming DA, Jameson GS, Mulcahy MF, Vaghefi H, Dudley MW, Holen KD, DeLuca A, Mittapalli RK, Munasinghe W, He L, Zalcberg JR, Ngan SY, Komarnitsky P, Michael M. Safety and tolerability of veliparib combined with capecitabine plus radiotherapy in patients with locally advanced rectal cancer: a phase 1b study. Lancet Gastroenterol Hepatol. 2017 Jun;2(6):418-426. doi: 10.1016/S2468-1253(17)30012-2. Epub 2017 Mar 27. PubMed PMID: 28497757.

Drinkwater N. Robert G. McKinnell, The Understanding, Prevention and Control of Human Cancer: The Historic Work and Lives of Elizabeth Cavert Miller and James A. Miller (Leiden and Boston: Brill, 2016), pp. xvi, 196, $50, hardback, ISBN: 9789004286795. Med Hist. 2017 Jan;61(1):152-153. doi: 10.1017/mdh.2016.121. PubMed Central PMCID: PMC5206955.

Ericksen SS, Wu H, Zhang H, Michael LA, Newton MA, Hoffmann FM, Wildman SA. Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening. J Chem Inf Model. 2017 Jul 24;57(7):1579-1590. doi: 10.1021/acs.jcim.7b00153. Epub 2017 Jul 12. PubMed PMID: 28654262.

Ertel KJ, Benefield D, Castaño-Diez D, Pennington JG, Horswill M, den Boon JA, Otegui MS, Ahlquist P. Cryo-electron tomography reveals novel features of a viral RNA replication compartment. Elife. 2017 Jun 27;6. pii: e25940. doi: 10.7554/eLife.25940. PubMed PMID: 28653620; PubMed Central PMCID: PMC5515581.

Foley TM, Payne SN, Pasch CA, Yueh AE, Van De Hey DR, Korkos DP, Clipson L, Maher ME, Matkowskyj KA, Newton MA, Deming DA. Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations. Mol Cancer Res. 2017 Feb 9;15(3):317-327. doi: 10.1158/1541-7786.MCR-16-0256. [Epub ahead of print] PubMed PMID: 28184015; PubMed Central PMCID: PMC5550373.

Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F. Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. J Immunol. 2017 Sep 1;199(5):1933-1941. doi: 10.4049/jimmunol.1700529. Epub 2017 Jul 28. PubMed PMID: 28754680; PubMed Central PMCID: PMC5568487.

Iwahori S, Umaña AC, VanDeusen HR, Kalejta RF. Human cytomegalovirus-encoded viral cyclin-dependent kinase (v-CDK) UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 proteins. J Biol Chem. 2017 Apr 21;292(16):6583-6599. doi: 10.1074/jbc.M116.773150. Epub 2017 Mar 13. PubMed PMID: 28289097; PubMed Central PMCID: PMC5399109.

Kalejta RF, Palmenberg AC. Gender parity trends for invited speakers at four prominent virology conference series. J Virol. 2017 Jun 7. pii: JVI.00739-17. doi: 10.1128/JVI.00739-17. [Epub ahead of print] PubMed PMID: 28592542; PubMed Central PMCID: PMC5533912.

Kraus RJ, Yu X, Cordes BA, Sathiamoorthi S, Iempridee T, Nawandar DM, Ma S, Romero-Masters JC, McChesney KG, Lin Z, Makielski KR, Lee DL, Lambert PF, Johannsen EC, Kenney SC, Mertz JE. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PLoS Pathog. 2017 Jun 15;13(6):e1006404. doi: 10.1371/journal.ppat.1006404. eCollection 2017 Jun. PubMed PMID: 28617871; PubMed Central PMCID: PMC5487075.

Liu C, Clark PA, Kuo JS, Kalejta RF. Human Cytomegalovirus-Infected Glioblastoma Cells Display Stem Cell-Like Phenotypes. mSphere. 2017 Jun 21;2(3).  pii: e00137-17. doi: 10.1128/mSphere.00137-17. eCollection 2017 May-Jun. PubMed PMID: 28656174; PubMed Central PMCID: PMC5480031.

Lubner SJ, Uboha NV, Deming DA. Primary and acquired resistance to biologic therapies in gastrointestinal cancers. J Gastrointest Oncol. 2017 Jun;8(3):499-512. doi: 10.21037/jgo.2017.01.16. Review. PubMed PMID: 28736637; PubMed Central PMCID: PMC5506279.

Ma SD, Tsai MH, Romero-Masters JC, Ranheim EA, Huebner SM, Bristol JA, Delecluse HJ, Kenney SC. Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential. J Virol. 2017 Mar 13;91(7). pii: e01928-16. doi: 10.1128/JVI.01928-16. Print 2017 Apr 1. PubMed PMID: 28077657; PubMed Central PMCID: PMC5355617.

Matrka MC, Watanabe M, Muraleedharan R, Lambert PF, Lane AN, Romick-Rosendale LE, Wells SI. Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis. PLoS One. 2017 May 30;12(5):e0177952. doi: 10.1371/journal.pone.0177952. eCollection 2017. PubMed PMID: 28558019.  PMCID:  PMC5448751

Meyers JM, Uberoi A, Grace M, Lambert PF, Munger K. Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation. PLoS Pathog. 2017 Jan 20;13(1):e1006171. doi: 10.1371/journal.ppat.1006171. PubMed PMID: 28107544; PubMed Central PMCID: PMC5287491.

Morris VK, Salem ME, Nimeiri H, Iqbal S, Singh P, Ciombor K, Polite B, Deming D, Chan E, Wade JL, Xiao L, Bekaii-Saab T, Vence L, Blando J, Mahvash A, Foo WC, Ohaji C, Pasia M, Bland G, Ohinata A, Rogers J, Mehdizadeh A, Banks K, Lanman R, Wolff RA, Streicher H, Allison J, Sharma P, Eng C. Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study. Lancet Oncol. 2017 Apr;18(4):446-453. doi: 10.1016/S1470-2045(17)30104-3. Epub 2017 Feb 18. PubMed PMID: 28223062.

Nawandar DM, Ohashi M, Djavadian R, Barlow E, Makielski K, Ali A, Lee D, Lambert PF, Johannsen E, Kenney SC. Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial Cells. J Virol. 2017 Mar 29;91(8). pii: e02438-16. doi: 10.1128/JVI.02438-16. Print 2017 Apr 15. PubMed PMID: 28179525; PubMed Central PMCID: PMC5375685.

Nowak K, Linzner D, Thrasher AJ, Lambert PF, Di WL, Burns SO. Absence of ?-chain in keratinocytes alters chemokine secretion resulting in reduced immune cell recruitment. J Invest Dermatol. 2017 Jun 17. pii: S0022-202X(17)31647-0. doi: 10.1016/j.jid.2017.05.024. [Epub ahead of print] PubMed PMID: 28634034.

Pang Y, Deng C, Geng S, Weng J, Lai P, Liao P, Zeng L, Lu Z, Zhang J, Du X. Premature exhaustion of mesenchymal stromal cells from myelodysplastic syndrome patients. Am J Transl Res. 2017 Jul 15;9(7):3462-3468. eCollection 2017. PubMed PMID: 28804562; PubMed Central PMCID: PMC5527260.

Pocock GM, Zimdars LL, Yuan M, Eliceiri KW, Ahlquist P, Sherer NM. Diverse activities of viral cis-acting RNA regulatory elements revealed using multicolor, long-term, single-cell imaging. Mol Biol Cell. 2017 Feb 1;28(3):476-487. doi: 10.1091/mbc.E16-08-0612. Epub 2016 Nov 30. PubMed PMID: 27903772; PubMed Central PMCID: PMC5341730

Price AM, Dai J, Bazot Q, Patel L, Nikitin PA, Djavadian R, Winter PS, Salinas CA, Barry AP, Wood KC, Johannsen EC, Letai A, Allday MJ, Luftig MA. Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection. Elife. 2017 Apr 20;6. pii: e22509. doi: 10.7554/eLife.22509. PubMed PMID: 28425914; PubMed Central PMCID: PMC5425254.

Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5431-5436. doi: 10.1073/pnas.1617035114. Epub 2017 Apr 10. PubMed PMID: 28396409; PubMed Central PMCID: PMC5448172.

Shishkova E, Zeng H, Liu F, Kwiecien NW, Hebert AS, Coon JJ, Xu W. Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition. Nat Commun. 2017 May 24;8:15571. doi: 10.1038/ncomms15571. PubMed PMID: 28537268; PubMed Central PMCID: PMC5458078.

Sievers CK, Grady WM, Halberg RB, Pickhardt PJ. New insights into the earliest stages of colorectal tumorigenesis. Expert Rev Gastroenterol Hepatol. 2017 Aug;11(8):723-729. doi: 10.1080/17474124.2017.1330150. Epub 2017 May 26. PubMed PMID: 28503955.

Spurgeon ME, Lambert PF. Human Papillomavirus and the Stroma: Bidirectional Crosstalk during the Virus Life Cycle and Carcinogenesis. Viruses. 2017 Aug 9;9(8). pii: E219. doi: 10.3390/v9080219. Review. PubMed PMID: 28792475; PubMed Central PMCID: PMC5580476.

Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AY, Chaudhuri J. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017 Jan;214(1):197-208. doi: 10.1084/jem.20160789. PubMed PMID: 28011866; PubMed Central PMCID: PMC5206498.

Voter AF, Killoran MP, Ananiev GE, Wildman SA, Hoffmann FM, Keck JL. A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility. SLAS Discov. 2017 May 1:2472555217712001. doi: 10.1177/2472555217712001. [Epub ahead of print] PubMed PMID: 28570838.

Wang Y, Wang Y, Chen G, Li Y, Xu W, Gong S. Quantum-Dot-Based Theranostic Micelles Conjugated with an Anti-EGFR Nanobody for Triple-Negative Breast Cancer Therapy. ACS Appl Mater Interfaces. 2017 Aug 28. doi: 10.1021/acsami.7b05654. [Epub ahead of print] PubMed PMID: 28845963.

Watters K, Inankur B, Gardiner JC, Warrick J, Sherer NM, Yin J, Palmenberg AC. Differential Disruption of Nucleocytoplasmic Trafficking Pathways by Rhinovirus 2A Proteases. J Virol. 2017 Mar 29;91(8). pii: e02472-16. doi: 10.1128/JVI.02472-16. Print 2017 Apr 15. PubMed PMID: 28179529; PubMed Central PMCID: PMC5375692.

Wille CK, Li Y, Rui L, Johannsen EC, Kenney SC. Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency. J Virol. 2017 Feb 14;91(5). pii: e01987-16. doi: 10.1128/JVI.01987-16. PubMed PMID: 28003489; PubMed Central PMCID: PMC5309966.

Wu CG, Chen H, Guo F, Yadav VK, Mcilwain SJ, Rowse M, Choudhary A, Lin Z, Li Y, Gu T, Zheng A, Xu Q, Lee W, Resch E, Johnson B, Day J, Ge Y, Ong IM, Burkard ME, Ivarsson Y, Xing Y. PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis. Cell Discov. 2017 Aug 8;3:17027. doi: 10.1038/celldisc.2017.27. eCollection 2017. PubMed PMID: 28884018; PubMed Central PMCID: PMC5586252.

Yang YC, Liem A, Lambert PF, Sugden B. Dissecting the regulation of EBV's BART miRNAs in carcinomas. Virology. 2017 May;505:148-154. doi: 10.1016/j.virol.2017.02.013. Epub 2017 Mar 1. PubMed PMID: 28259048; PubMed Central PMCID: PMC5504693.

Zhang F, Barns K, Hoffmann FM, Braun DR, Andes DR, Bugni TS. Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris. J Nat Prod. 2017 Aug 25. doi: 10.1021/acs.jnatprod.7b00328. [Epub ahead of print] PubMed PMID: 28840714.

Zhang J, Kong G, Rajagopalan A, Lu L, Song J, Hussaini M, Zhang X, Ranheim EA, Liu Y, Wang J, Gao X, Chang YI, Johnson KD, Zhou Y, Yang D, Bhatnagar B, Lucas DM, Bresnick EH, Zhong X, Padron E, Zhang J. p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia. Blood. 2017 Jan 19;129(3):358-370. doi: 10.1182/blood-2016-06-719237. PubMed PMID: 27815262; PubMed Central PMCID: PMC5248933.

Zhu F, Hwang B, Miyamoto S, Rui L. Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma. Mol Cancer Res. 2017 Mar;15(3):348-357. doi: 10.1158/1541-7786.MCR-16-0344. Epub 2016 Dec 28. PubMed PMID: 28031410; PubMed Central PMCID: PMC5473959.

Zumwalde NA, Sharma A, Xu X, Ma S, Schneider CL, Romero-Masters JC, Hudson AW, Gendron-Fitzpatrick A, Kenney SC, Gumperz JE. Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model. JCI Insight. 2017 Jul 6;2(13). pii: 93179. doi: 10.1172/jci.insight.93179. [Epub ahead of print] PubMed PMID: 28679955; PubMed Central PMCID: PMC5499361.

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