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2012 McArdle Publications

Click on citation to go to PubMed for article abstract.

Alexander, C. M., Goel, S., Fakhraldeen, S. A., and Kim, S.  Wnt Signaling in Mammary Glands:  Plastic Cell Fates and Combinatorial Signaling.  Cold Spring Harbor Perspect. Biol., 4(10):pii: a008037, 2012.

Amos-Landgraf, J. M., Clipson, L., Newton, M. A., and Dove, W. F.  The Many Ways to Open the Gate to Colon Cancer.  Cell Cycle, 11:  1261-1262, 2012.

Amos-Landgraf, J. M., Irving, A. A., Hartman, C., Hunter, A., Laube, B., Chen, X., Clipson, L., Newton, M. A., and Dove, W. F.  Monoallelic Silencing and Haploinsufficiency in Early Murine Intestinal Neoplasms.  Proc. Natl. Acad. Sci. USA, 109: 2060-2065, 2012.

Arjan-Odedra, S., Swanson, C. M., Sherer, N. M., Wolinsky, S. M., and Malim, M. H.  Endogenous MOV10 Inhibits the Retrotransposition of Endogenous Retroelements But Not the Replication of Exogenous Retroviruses.  Retrovirology, 9:53, 2012.

Bilger, A., Poli, E., Schneider, A., Baus, R., and Drinkwater, N.  The Hcs7 Mouse Liver Cancer Modifier Maps to a 3.3 Mb Region Carrying the Strong Candidate Ifi202bIn:  A. Julianov (Ed.), Liver Tumors, pp. 19-36.  Rijeka, Croatia: Intech, 2012. (http://www.intechopen.com/books/liver-tumors)

Bonilla-Delgado, J., Bulut, G., Liu, X., Cortés-Malagón, E. M., Schlegel, R., Flores-Maldonado, C., Contreras, R. G., Chung, S.-H., Lambert, P. F., Üren, A., and Gariglio, P.  The E6 Oncoprotein from HPV16 Enhances the Canonical Wnt/β-Catenin Pathway in Skin Epidermis in Vivo.  Mol. Cancer Res., 10: 250-258, 2012.

Burgess, R. R.  Fusion Tags: A Collection of Papers.  Protein Expr. Purif., 81:  A1-A2, 2012.

Chiu, Y.-F., Sugden, B., Chang, P.-J., Chen, L.-W., Lin, Y.-J., Lan, Y.-C., Lai, C.-H., Liou, J.-Y., Liu, S.-T., and Hung, C.-H.  Characterization and Intracellular Trafficking of Epstein-Barr Virus BBLF1, a Protein Involved in Virion Maturation.  J. Virol., 86: 9647-9655, 2012.

Das, S., Becker, B. N., Hoffmann, F. M., and Mertz, J. E.  Reversal of Transforming Growth Factor-β Induced Epithelial-to-Mesenchymal Transition and the ZEB Proteins.  Fibrogenesis Tissue Repair, 5(Suppl1): S28, 2012.

Diaz, A., and Ahlquist, P.  Role of Host Reticulon Proteins in Rearranging Membranes for Positive-Strand RNA Virus Replication.  Curr. Opin. Microbiol., 15: 519-524, 2012.

Diaz, A., Gallei, A., and Ahlquist, P.  Bromovirus RNA Replication Compartment Formation Requires Concerted Action of 1a’s Self-Interacting RNA Capping and Helicase Domains.  J. Virol., 86: 821-834, 2012.

Dove, W., and Susman, M.  Retrospective.  James F. Crow (1916-2012).  Science, 335:  812, 2012.

Drinkwater, N. R., and Gould, M. N.  The Long Path from QTL to Gene.  PLoS Genet., 8(9):e1002975, 2012.

Du, J., Wang, J., Kong, G., Jiang, J., Zhang, J., Liu, Y., Tong, W., and Zhang, J.  Signaling Profiling at the Single-Cell Level Identifies a Distinct Signaling Signature in Murine Hematopoietic Stem Cells.  Stem Cells, 30: 1447-1454, 2012.

Dziurzynski, K., Chang, S. M., Heimberger, A. B., Kalejta, R. F., McGregor Dallas, S. R., Smit, M., Soroceanu, L., Cobbs, C. S., the HCMV and Gliomas Symposium.  Consensus on the Role of Human Cytomegalovirus in Glioblastoma.  Neuro Oncol., 14: 246-255, 2012.

Esch, A. M., Thompson, N. E., Lamberski, J. A., Mertz, J. E., and Burgess, R. R.  Production and Characterization of Monoclonal Antibodies to Estrogen-Related Receptor Alpha (ERRα) and Use in Immunoaffinity Chromatography.  Protein Expr. Purif., 84: 47-58, 2012.

Goel, S., Chin, E. N., Fakhraldeen, S. A., Berry, S. M., Beebe, D. J., and Alexander, C. M.  Both LRP5 and LRP6 Receptors Are Required to Respond to Physiological Wnt Ligands in Mammary Epithelial Cells and Fibroblasts.  J. Biol. Chem., 287: 16454-16466, 2012.

Gunsalus, K. T. W., Wagoner, M. P., Meyer, K., Potter, W. B., Schoenike, B., Kim, S., Alexander, C. M., Friedl, A., and Roopra, A.  Induction of the RNA Regulator LIN28A Is Required for the Growth and Pathogenesis of RESTless Breast Tumors.  Cancer Res., 72: 3207-3216, 2012.

Hagemeier, S. R., Barlow, E. A., Meng, Q., and Kenney, S. C.  The Cellular Ataxia Telangiectasia-Mutated Kinase Promotes Epstein-Barr Virus Lytic Reactivation in Response to Multiple Different Types of Lytic Reactivation-Inducing Stimuli.  J. Virol., 86: 13360-13370, 2012.

Hoebe, E. K., Wille, C., Hopmans, E. S., Robinson, A. R., Middeldorp, J. M., Kenney, S. C., and Greijer, A. E.  Epstein-Barr Virus Transcription Activator R Upregulates BARF1 Expression by Direct Binding to Its Promoter, Independent of Methylation.  J. Virol., 86: 11322-11332, 2012.

Hoskins, E. E., Morreale, R. J., Werner, S. P., Higginbotham, J. M., Laimins, L. A., Lambert, P. F., Brown, D. R., Gillison, M. L., Nuovo, G. J., Witte, D. P., Kim, M.-O., Davies, S. M., Mehta, P. A., Kovacic, M. B., Wikenheiser-Brokamp, K. A., and Wells, S. I.  The Fanconi Anemia Pathway Limits Human Papillomavirus Replication.  J. Virol., 86: 8131-8138, 2012.

Huang, H.-S., and Lambert, P. F.  Use of an in Vivo Animal Model for Assessing the Role of Integrin α6β4 and Syndecan-1 in Early Steps in Papillomavirus Infection.  Virology, 433: 395-400, 2012.

Huang, H.-S., Pyeon, D., Pearce, S. M., Lank, S. M., Griffin, L. M., Ahlquist, P., and Lambert, P. F.  Novel Antivirals Inhibit Early Steps in HPV Infection.  Antiviral Res., 93: 280-287, 2012.

Ibarra Sierra, E., Díaz Chávez, J., Cortés-Malagón, E. M., Uribe-Figueroa, L., Hidalgo-Miranda, A., Lambert, P. F., and Gariglio, P.  Differential Gene Expression between Skin and Cervix Induced by the E7 Oncoprotein in a Transgenic Mouse Model.  Virology, 433: 337-345, 2012.

Jabbar, S. F., Park, S., Schweizer, J., Berard-Bergery, M., Pitot, H. C., Lee, D., and Lambert, P. F.  Cervical Cancers Require the Continuous Expression of the Human Papillomavirus Type 16 E7 Oncoprotein Even in the Presence of the Viral E6 Oncoprotein.  Cancer Res., 72: 4008-4016, 2012.

Johnson, K. D., Hsu, A. P., Ryu, M.-J., Wang, J., Gao, X., Boyer, M. E., Liu, Y., Lee, Y., Calvo, K. R., Keles, S., Zhang, J., Holland, S. M., and Bresnick, E. H.  Cis-Element Mutated in GATA2-Dependent Immunodeficiency Governs Hematopoiesis and Vascular Integrity.  J. Clin. Invest., 122:  3692-3704, 2012.

Kim, S., Roopra, A., and Alexander, C. M.  A Phenotypic Mouse Model of Basaloid Breast Tumors.  PLoS One, 7(2):e30979, 2012.

Klos, K. S., Kim, S., and Alexander, C. M.  Genotoxic Exposure during Juvenile Growth of Mammary Gland Depletes Stem Cell Activity and Inhibits Wnt Signaling.  PLoS One, 7(11):e49902, 2012.

Kuzembayeva, M., Chiu, Y.-F., and Sugden, B.  Comparing Proteomics and RISC Immunoprecipitations to Identify Targets of Epstein-Barr Viral miRNAs.  PLoS One, 7(10):e47409, 2012.

Lee, J. S., Cella, M., McDonald, K. G., Garlanda, C., Kennedy, G. D., Nukaya, M., Mantovani, A., Kopan, R., Bradfield, C. A., Newberry, R. D., and Colonna, M.  AHR Drives the Development of Gut ILC22 Cells and Postnatal Lymphoid Tissues via Pathways Dependent on and Independent of Notch.  Nat. Immunol., 13: 144-151, 2012.

Lee, S. H., Kalejta, R. F., Kerry, J., Semmes, O. J., O’Connor, C. M., Khan, Z., Garcia, B. A., Shenk, T., and Murphy, E.  BclAF1 Restriction Factor Is Neutralized by Proteasomal Degradation and microRNA Repression during Human Cytomegalovirus Infection.  Proc. Natl. Acad. Sci. USA, 109: 9575-9580, 2012.

Lobocka, M., and Szybalski, W. T.  Bacteriophages, Part A. Preface.  Adv. Virus Res., 82:  xiii-xv, 2012.

Lobocka, M., and Szybalski, W. T.  Phages.  Preface.  Adv. Virus Res., 83:  xvii-xviii, 2012.

Ma, S.-D., Yu, X., Mertz, J. E., Gumperz, J. E., Reinheim, E., Zhou, Y., Tang, W., Burlingham, W. J., Gulley, M. L., and Kenney, S. C.  An Epstein-Barr Virus (EBV) Mutant with Enhanced BZLF1 Expression Causes Lymphomas with Abortive Lytic EBV Infection in a Humanized Mouse Model.  J. Virol., 86: 7976-7987, 2012.

Malecki, M., and Szybalski, W.  Isolation of Single, Intact Chromosomes from Single, Selected Ovarian Cancer Cells for in Situ Hybridization and Sequencing.  Gene, 493: 132-139, 2012.

McCool, K. W., and Miyamoto, S.  DNA Damage-dependent NF-κB Activation:  NEMO Turns Nuclear Signaling Inside Out.  Immunol. Rev., 246:  311-326, 2012.

Mezrich, J. D., Nguyen, L. P., Kennedy, G., Nukaya, M., Fechner, J. H., Zhang, X., Xing, Y., and Bradfield, C. A.  SU5416, a VEGF Receptor Inhibitor and Ligand of the AHR, Represents a New Alternative for Immunomodulation.  PLoS One, 7(9):e44547, 2012.

Norby, K., Chiu, Y.-F., and Sugden, B.  Monitoring Plasmid Replication in Live Mammalian Cells over Multiple Generations by Fluorescence Microscopy.  J. Vis. Exp., (70):e4305, 2012.

Paschos, G. K., Ibrahim, S., Song, W.-L., Kunieda, T., Grant, G., Reyes, T. M., Bradfield, C. A., Vaughan, C. H., Eiden, M., Masoodi, M., Griffin, J. L., Wang, F., Lawson, J. A., and FitzGerald, G. A.  Obesity in Mice with Adipocyte-specific Deletion of Clock Component Arntl.  Nat. Med., 18: 1768-1777, 2012.

Pauly, S. K., Fechner, J. H., Zhang, X., Torrealba, J., Bradfield, C. A., and Mezrich, J. D.  The Aryl Hydrocarbon Receptor Influences Transplant Outcomes in Response to Environmental Signals.  Toxicol. Environ. Chem., 94:  1175-1187, 2012.

Peebles, D. D., Soref, C. M., Copp, R. R., Thunberg, A. L., and Fahl, W. E.  ROS-Scavenger and Radioprotective Efficacy of the New PrC-210 Aminothiol.  Radiat. Res., 178: 57-68, 2012.

Penkert, R. R., and Kalejta, R. F.  Tale of a Tegument Transactivator:  The Past, Present and Future of Human CMV pp71.  Future Virol., 7:  855-869, 2012.

Phalora, P. K., Sherer, N. M., Wolinsky, S. M., Swanson, C. M., and Malim, M. H.  HIV-1 Replication and APOBEC3 Antiviral Activity Are Not Regulated by P Bodies.  J. Virol., 86:  11712-11724, 2012.

Pirone, J. R., D’Arcy, M., Stewart, D. A., Hines, W. C., Johnson, M., Gould, M. N., Yaswen, P., Jerry, D. J., Schneider, S. S., and Troester, M. A.  Age-Associated Gene Expression in Normal Breast Tissue Mirrors Qualitative Age-at-Incidence Patterns for Breast Cancer.  Cancer Epidemiol. Biomarkers Prev., 21: 1735-1744, 2012.

Powell, E., Shanle, E., Brinkman, A., Li, J., Keles, S., Wisinski, K. B., Huang, W., and Xu, W.  Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERa and ERβ.  PLoS One, 7(2):e30993, 2012.

Pratt, Z. L., and Sugden, B.  How Human Tumor Viruses Make Use of Autophagy.  Cells, 1:  617-630, 2012.

Pratt, Z. L., Zhang, J., and Sugden, B.  The Latent Membrane Protein 1 (LMP1) Oncogene of Epstein-Barr Virus Can Simultaneously Induce and Inhibit Apoptosis in B Cells.  J. Virol., 86: 4380-4393, 2012.

Rajbhandari, P., Finn, G., Solodin, N. M., Singarapu, K. K., Sahu, S. C., Markley, J. L., Kadunc, K. J., Ellison-Zelski, S. J., Kariagina, A., Haslam, S. Z., Lu, K. P., and Alarid, E. T.  Regulation of Estrogen Receptor α N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1.  Mol. Cell. Biol., 32: 445-457, 2012.

Ranganathan, P., Clark, P. A., Kuo, J. S., Salamat, M. S., and Kalejta, R. F.  Significant Association of Multiple Human Cytomegalovirus Genomic Loci with Glioblastoma Multiforme Samples.  J. Virol., 86: 854-864, 2012.

Robinson, A. R., Kwek, S. S., and Kenney, S. C.  The B-Cell Specific Transcription Factor, Oct-2, Promotes Epstein-Barr Virus Latency by Inhibiting the Viral Immediate-Early Protein, BZLF1.  PLoS Pathog., 8(2):e1002516, 2012.

Ryan, J. L., Shen, Y.-J., Morgan, D. R., Thorne, L. B., Kenney, S. C., Dominguez, R. L., and Gulley, M. L.  Epstein-Barr Virus Infection Is Common in Inflamed Gastrointestinal Mucosa.  Dig. Dis. Sci., 57: 1887-1898, 2012.

Ryu, M.-J., Liu, Y., Zhong, X., Du, J., Peterson, N., Kong, G., Li, H., Wang, J., Salamat, S., Chang, Q., and Zhang, J.  Oncogenic Kras Expression in Postmitotic Neurons Leads to S100A8-S100A9 Protein Overexpression and Gliosis.  J. Biol. Chem., 287:  22948-22958, 2012.

Sharma, D., Eichelberg, M. R., Haag, J. D., Meilahn, A. L., Muelbl, M. J., Schell, K., Smits, B. M. G., and Gould, M. N.  Effective Flow Cytometric Phenotyping of Cells Using Minimal Amounts of Antibody.  BioTechniques, 53:  57-60, 2012.

Shin, M.-K., Pitot, H. C., and Lambert, P. F.  Pocket Proteins Suppress Head and Neck Cancer.  Cancer Res., 72: 1280-1289, 2012.

Shin, M.-K., Sage, J., and Lambert, P. F.  Inactivating All Three Rb Family Pocket Proteins Is Insufficient to Initiate Cervical Cancer.  Cancer Res., 72: 5418-5427, 2012.

Siddens, L. K., Larkin, A., Krueger, S. K., Bradfield, C. A., Waters, K. M., Tilton, S. C., Pereira, C. B., Löhr, C. V., Arlt, V. M., Phillips, D. H., Williams, D. E., and Baird, W. M.  Polycyclic Aromatic Hydrocarbons as Skin Carcinogens:  Comparison of Benzo[a]pyrene, Dibenzo[def,p]chrysene and Three Environmental Mixtures in the FVB/N Mouse.  Toxicol. Appl. Pharmacol., 264: 377-386, 2012. 

Smits, B. M. G., Traun, B. D., Devries, T. L., Tran, A., Samuelson, D., Haag, J. D., and Gould, M.  An Insulator Loop Resides between the Synthetically Interacting Elements of the Human/Rat Conserved Breast Cancer Susceptibility Locus MCS5A/Mcs5a.  Nucleic Acids Res., 40: 132-147, 2012.

Soref, C. M., Hacker, T. A., and Fahl, W. E.  A New Orally Active, Aminothiol Radioprotector-Free of Nausea and Hypotension Side Effects at Its Highest Radioprotective Doses.  Int. J. Radiat. Oncol., 82: e701-e707, 2012.

Thliveris, A. T., Clipson, L., Sommer, L. L., Schoenike, B. A., Hasenstein, J. R., Schlamp, C. L., Alexander, C. M., Newton, M. A., Dove, W. F., and Amos-Landgraf, J. M.  Regulated Expression of Chromobox Homolog 5 Revealed in Tumors of ApcMin/+ ROSA11 Gene Trap Mice.  G3 (Bethesda), 2:  569-578, 2012.

Togtema, M., Pichardo, S., Jackson, R., Lambert, P. F., Curiel, L., and Zehbe, I.  Sonoporation Delivery of Monoclonal Antibodies against Human Papillomavirus 16 E6 Restores p53 Expression in Transformed Cervical Keratinocytes.  PLoS One, 7(11):e50730, 2012.

Tomasini-Johansson, B. R., Johnson, I. A., Hoffmann, F. M., and Mosher, D. F.  Quantitative Microtiter Fibronectin Fibrillogenesis Assay:  Use in High Throughput Screening for Identification of Inhibitor Compounds.  Matrix Biol., 31: 360-367, 2012.

Wang, Q., Yang, L., Alexander, C., and Temple, S.  The Niche Factor Syndecan-1 Regulates the Maintenance and Proliferation of Neural Progenitor Cells during Mammalian Cortical Development.  PLoS One, 7(8):e42883, 2012. [Erratum in: PLoS One, 7(11), 2012.]

Wen, Z., Pyeon, D., Wang, Y., Lambert, P., Xu, W., and Ahlquist, P.  Orphan Nuclear Receptor PNR/NR2E3 Stimulates p53 Functions by Enhancing p53 Acetylation.  Mol. Cell. Biol., 32: 26-35, 2012.

Wu, J., and Xu, W.  Histone H3R17me2a Mark Recruits Human RNA Polymerase-Associated Factor 1 Complex to Activate Transcription.  Proc. Natl. Acad. Sci. USA, 109: 5675-5680, 2012.

Xing, Y., Nukaya, M., Satyshur, K. A., Jiang, L., Stanevich, V., Korkmaz, E. N., Burdette, L., Kennedy, G. D., Cui, Q., and Bradfield, C. A.  Identification of the Ah-Receptor Structural Determinants for Ligand Preferences.  Toxicol. Sci., 129: 86-97, 2012.

Young, E. W. K., Pak, C., Kahl, B. S., Yang, D. T., Callander, N. S., Miyamoto, S., and Beebe, D. J.  Microscale Functional Cytomics for Studying Hematologic Cancers.  Blood, 119: e76-e85, 2012.

Yu, X., McCarthy, P. J., Wang, Z., Gorlen, D. A., and Mertz, J. E.  Shutoff of BZLF1 Gene Expression Is Necessary for Immortalization of Primary B Cells by Epstein-Barr Virus.  J. Virol., 86: 8086-8096, 2012.

Zhang, J., Diaz, A., Mao, L., Ahlquist, P., and Wang, X.  Host Acyl Coenzyme A Binding Protein Regulates Replication Complex Assembly and Activity of a Positive-Strand RNA Virus.  J. Virol., 86: 5110-5121, 2012.

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