Semester I; 2 credits. This course is the first in a series of courses offered by the Department of Oncology covering much of the field of basic oncology. The objective of Oncology 401 is to introduce the student to the biological processes and mechanisms associated with the characteristics of neoplasia. Oncology 401 is given every fall semester and is open to both graduate and undergraduate students. Prerequisites: Biology and organic chemistry or consent of instructor. Biochemistry, genetics, and physiology recommended.
Instructors – Paul Lambert and Richard Halberg
Text: H.C. Pitot, Fundamentals of Oncology, 4th edition, Marcel Dekker, Inc., NY, 2002.
Semester II; 1 credit. Crosslisted with Microbiology 545. Current topics in medical, agricultural, and industrial biotechnology are covered. Content varies from year to year.
Prerequisites: Biochemistry 501 and Genetics 466 or equivalent.
Instructor: Eric Johnson
Semester I; 3 credits. Crosslisted with Molecular & Environmental Toxicology 625, Medicine 625, Pathology 625, Pharmacology 625, Pharmaceutical Sciences 625, and Population Health Sciences 625. A basic course on the principles of toxicology and biochemical mechanisms of toxicity in mammalian species, including humans. Correlation between morphological and functional changes caused by toxicants in different organs of the body.
Semester I; 3 credits. Crosslisted with Microbiology 640 and Plant Pathology 640. Lectures on bacterial and animal viruses, their structure, multiplication and genetics.
Prerequisites: Introductory courses in bacteriology, biochemistry, and genetics, or consent of instructor.
Instructors: Paul Ahlquist, Nathan Sherer, Robert Kalejta
Semester II in odd-numbered years; 2 credits. A course on the theory and practice of protein purification. Topics covered include conventional and recent protein fractionation techniques; enzyme assays, handling, and characterization; purification strategy; and overproduction of cloned gene products. The emphasis is on micro and laboratory scale purifications. Prerequisites: Biochemistry and physical chemistry or consent of instructor. Instructor: Yongna Xing and Richard R. Burgess.
Semester I; 3 credits. Viral, chemical, and physical factors involved in tumor formation in humans and experimental animals; biology and biochemistry of neoplasia, both in vivo and in vitro.
Prerequisites: Oncology 401 or equivalent, organic chemistry, biochemistry, cell biology, virology, or consent of instructor.
Instructors: Wei Xu (course director), Caroline Alexander, Chris Bradfield, Paul Lambert, Jing Zhang.
Semester II; 1 credit. A review and discussion of the fundamentals of good scientific communication and ethical issues in science. Prerequisites: Graduate standing and consent of instructor. Instructor: Janet Mertz.
Semester II; 2 credits. A review and discussion of the current literature on topics related to cancer biology. The emphasis is on the development of skills in data analysis and interpretation, proposal writing, and oral presentation. Prerequisites: Open to first-year graduate students only. Instructor: varies.
Semesters I and II; 1 credit. Presentations of original research in areas related to viral oncology and cancer biology. To aid students in presentation of data. Prerequisites: Graduate standing and consent of instructor. Instructor: varies.
Semesters I, II, Summer; 1-12 credits.