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McArdle News

2015

Shigeki Miyamoto, Ph.D., McArdle Laboratory for Cancer Research, and David Beebe, Ph.D., Biomedical Engineering, UW-Madison, recently published news of an important advance in efforts to tailor medical treatment plans to individual patients by creating a "tumor in a dish" that can accurately anticipate a multiple myeloma patient's response to a drug.

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On Friday, May 1, 2015, Christopher Bradfield, Ph.D., Professor of Oncology at the McArdle Laboratory for Cancer Research was appointed interim director of the Wisconsin Institute for Discovery (WID) by UW-Madison Vice Chancellor for Research and Graduate Education, Marsha Mailick.

Click here to learn more about Dr. Bradfield's appointment

The McArdle Laboratory for Cancer Research would like to say THANK YOU to the Freedom High School Student Council Members and others who raised $2,800 for research at the McArdle Laboratory for Cancer Research.  Each year, the Freedom High School student council hosts a formal dance to acknowledge various clubs throughout the school.  Court members fundraise and seek out donations for about a week before the dance (and the court members who raise the greatest amount reign as King and Queen!).  All proceeds are then sent to the McArdle Laboratory.

Freedom Schools chose McArdle Laboratory as the recipient of this fundraiser because they appreciate that all donations that McArdle receives go directly to cancer research.  We would like to thank everyone involved in this event for your support.  This contribution provides critical support to our efforts to identify the causes of cancer and to develop more effective approaches for preventing and treating cancer.  The research we perform in the McArdle Laboratory would not be possible without the generous support of you and many others.

The McArdle Laboratory for Cancer Research would like to say THANK YOU to Verona Area School and community members who teamed up with Gray’s Tied House of Verona to sponsor their 10th Annual “Night of Hope”.  All proceeds from this event were donated to cancer research at the McArdle Laboratory in honor of all Verona Area School District families who have been affected by cancer.  This year over $5,700 was raised; over the last ten years, this fundraiser has contributed over $33,000 to the McArdle Laboratory for Cancer Research.

We would like to thank everyone involved in this event for your continued support.  A special thank you to the Verona Area School staff who organized the event, to Gray’s Tied House for hosting the event, and to everyone who donated money toward this fundraiser.  This contribution provides critical support to our efforts to identify the causes of cancer and to develop more effective approaches for preventing and treating cancer.  The research we perform in the McArdle Laboratory would not be possible without the generous support of you and many others.

Dr. Elizabeth Szybalski, long-time scientist at the McArdle Laboratory for Cancer Research, passed away on Thursday, April 23, 2015 after a long illness.  She was 87 years old.  Elizabeth was born and raised in Philadelphia, Pennsylvania, the daughter of Mabel H. Hunter and historic Orphan-Court Justice, the Honorable David G. Hunter.  She showed a strong intellect and a keen interest in science even as a young girl.  After receiving a BS degree in physics from Duke University, Elizabeth went on to earn MS and PhD degrees in microbiology at the University of Pennsylvania at a time when there were very few women in science.  Elizabeth met her future husband, Dr. Waclaw Szybalski, at Cold Spring Harbor Laboratory in 1952.  They were married in 1955.  She worked as a microbiologist at the University of Pennsylvania and in industry for several years before moving to Madison in 1960 with her husband.  For over 25 years Elizabeth and Waclaw worked together, carrying out ground-breaking research in genetics and molecular biology at the McArdle Laboratory for Cancer Research.  Her major contributions were toward creating the new field of gene therapy by performing the first-ever transfection (genetic transformation) of human cells, and developing a means of selecting for cells transfected with the human HPRT gene (encoding HPRT, also abbreviated as IMPPase) using “HAT” selection media, designed and named HAT by Elizabeth.  This became a commonplace method for introducing genes of interest into genomes of mammalian cells.  Among her other major contributions was the physical mapping of the bacterial (Escherichia coli) bio operon by electron microscopy.  Elizabeth is survived by her husband Waclaw and her children Barbara (Larry) Hunter-Sandor and Stefan Hunter Szybalski.

PBS will air a three-part documentary directed by award-winning filmmaker Barak Goodman and executive produced by Ken Burns, Cancer: The Emperor of All Maladies, based on the Pulitzer Prize-winning book. The series is described as "the most comprehensive documentary on a single disease ever made." It will be aired on Wisconsin Public Television (WPR) starting tonight, March 30, 2015 at 8:00 p.m. (You can visit the WPT site to find more information for your local station).

In conjunction with the film, WPT will also broadcast a series of lectures by UW-Madison cancer researchers. The lectures are part of WPT's "University Place" series. WPT will broadcast the following lectures and all are available are available to watch free. (Find the upcoming broadcast dates and learn how you can watch the lectures online):

  • How McArdle Scientists Found the Causes of Cancer with Oncology Professor Bill Sugden from the McArdle Laboratory for Cancer Research on Wednesday, April 1, at 4 p.m. and Monday, April 6, at 9 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Cancer Research Milestones at McArdle Lab with Professor Emeritus Henry Pitot on Thursday, April 2, at 4 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Diagnosing and Treating Prostate Cancer with Urology Professor David Jarrard on Friday, April 3, at 4 p.m.
  • Finding New Targets for Cancer Drugs with Professor Emeritus Dick Burgess from the McArdle Laboratory for Cancer Research on Monday, April 6, at 4:05 p.m. (in conjunction with McArdle Laboratory for Cancer Research's 75th Anniversary)
  • Mouse Models of Colon Cancer with Research Assistant Jamie Hadac on Tuesday, April 7, at 4 p.m.
  • Cancer Stem Cells Model Brain Tumor Treatments with Assistant Scientist Paul Clark from the Brain Tumor Research Laboratory on Wednesday, April 8, at 3:45 p.m.

The newly formed McArdle Alumni Advisory Board is comprised of about 30 alumni whom we believe represent the breadth and diversity of the >1500 graduate students and postdocs/scientists trained in McArdle over the last 75 years. Members of this advisory board all are highly successful alumni in academics, business and governmental organizations. They were active participants while at McArdle, have maintained contact with McArdle, and appreciate the positive effects of their training and time in Madison. These alumni are proud of their association with McArdle and have graciously agreed to help us improve our programs and be ambassadors for McArdle.

Click here for more information about our McArdle Alumni Advisory Board and it's members.

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